Y Chromosome Marker Development
There are certain circumstances whereby Y chromosome polymorphisms may need to be employed:

1. Identification of the genetic profile of the male component in mixed male/female specimens in which the female fraction is present in overwhelming quantities because:
   • Very few male cells were deposited during the incident due to azoospermic or oligospermic perpetrators or subsequent to oral sodomy in which the presence of trace numbers of buccal epithelial cells from the perpetrator may be present.
   • The amount of male cell equivalents is limited due to degradation or loss of the sample subsequent to deposition.
2. In sexual assaults, obviation of the need for the time-consuming and oft-times inefficient differential extraction procedure for the separation of sperm and none-sperm fractions.
3. Determination of the numbers of semen donors in multiple rape cases.
4. In criminal paternity analysis or disaster victim identification, determination of the haplotype of a missing individual by typing a male relative such as a son, brother, father, uncle or nephew.
5. The provision of increased statistical discrimination in mixture or kinship analysis cases in which the likelihood ratio obtained from autosomal markers is insufficient for identification purposes.

For More Information

Jack Ballantyne
Department of Chemistry, CH 117
University of Central Florida
Orlando, FL 32816
Telephone: 407-823-0163
FAX: 407-823-2252
E-Mail: jballant@mail.ucf.edu